Among the demands are better treatment of employees of color, a $15 minimum wage and more personal protective equipment.
Amazon, Instacart and Whole Foods face backlash from workers concerned about safe working conditions.
As the transit strike continues in France, residents are turning to alternative transportation arrangements.
There are some concessions the union had been pushing for, but the closure of the Lordstown, Ohio, plant remains a sticking point.
"We're getting little pennies compared to [GM executives]," one worker told Marketplace's Tracey Samuelson.
The UAW strike across the country could cost General Motors upwards of $100 million a day.
Workers shut down 33 manufacturing plants in nine states across the U.S., as well as 22 parts distribution warehouses.
The United Automobile Workers told its members it would increase strike pay from $200 a week to $275 by January.
The vote comes as U.S. Steel and ArcelorMittal are in union contract negotiations.
"I will be the greatest jobs president that God ever created."