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Jun 23, 2026

Why this Silicon Valley priest wants to teach AI right from wrong

Father Brendan McGuire of St. Simon’s Parish in Los Altos, California, discusses why he helped Anthropic draft its “Claude Constitution” and why the Vatican is engaging in the broader conversation around ethical AI.

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Why this Silicon Valley priest wants to teach AI right from wrong
Alberto Pizzoli/AFP via Getty Images

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In late May, Pope Leo XIV released Magnifica Humanitas. His first papal encyclical is an appeal for a more human-centered approach to artificial intelligence. Joining him at the Vatican for the unveiling was Anthropic co-founder, Chris Olah, and Father Brendan McGuire, pastor at St. Simon parish in Silicon Valley.

McGuire joined the priesthood after a career in tech and co-founded the Institute of Technology, Ethics and Culture — a joint initiative of the Vatican and Santa Clara University. He's one of a handful of religious leaders Anthropic has consulted on building ethics into AI.

Marketplace’s Meghan McCarty Carino spoke with Father Brendan about his experience as a spiritual advisor to AI.

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Why this Silicon Valley priest wants to teach AI right from wrong